papers

Self-assembled intelligent nano-delivery system with targeting for cascade anti-tumor therapy

Single antitumor therapy is difficult to completely cure the tumor, and there is a risk of metastasis and recurrence. Based on this, we proposed a cascade antitumor therapy. Firstly, self-assembly PdCl 2 was guided by lanreotide to form Pd nano-cubes by simulating biomineralization for antitumor photothermal therapy. Su...

Highly active nanoreactors for regulating tumor microenvironment and antitumor therapy

The tumor microenvironment is complex and changeable, so the design of nano-delivery system for tumor microenvironment has attracted wide attention. Based on this, we designed an intelligent nano-reactor for the characteristics of acidic pH and hypoxia in tumor microenvironment. Firstly, the silver nanocubes was synthes...

Knowledge Flow Theory and Modeling in Mechanical System Integration Design

The competition in the manufacturing industry is already the competition in design, and the design competition is, to a large extent, the competition of introducing new technologies to make products with new performance (increasing value). The basis for supporting competition is knowledge and the ability to acquire new...

Drug resistance and creating effective pharmaceuticals by predicting mutations

Whether it is a drug-resistant strain of bacteria or cancer cells that no longer react to the drugs, diverse mutations make cells resistant to chemicals and second generation approaches are needed. Drug resistance is a problem when treating diseases caused by bacteria, viruses and cancers. Creating a way to obtain data...