papers

Vitexin and isovitexin from the Leaves of Ficus deltoidea with in-vivo α-glucosidase inhibition

Ethnopharmacological relevance The leaves of Ficus deltoidea are used as a traditional medicine by diabetes patients in Malaysia. Aim of the study The objective of the study is to identify and evaluate bioactive constituents with in vivo -glucosidase inhibition. Materials and Methods The partitioned extracts, subfracti...

Design of controlled-release solid dosage forms of alginate and chitosan using microwave

The influence of microwave irradiation on the drug release properties of alginate, alginatechitosan and chitosan beads was investigated. The beads were prepared with the highest possible concentration of polymer by an extrusion method. Sulphathiazole was selected as a model drug. The beads were subjected to microwave i...

Pectin Matrix as Oral Drug Delivery Vehicle for Colon Cancer Treatment

Colon cancer is the fourth most common cancer globally with 639,000 deaths reported annually. Typical chemotherapy is provided by injection route to reduce tumor growth and metastasis. Recent research investigates the oral delivery profiles of chemotherapeutic agents. In comparison to injection, oral administration of ...

Sodium carboxymethylcellulose scaffolds and their physicochemical effects on partial thickness wound

This study investigated critical physicochemical attributes of low (LV), medium (MV) and high molecular weight (HV) sodium carboxymethylcellulose (SCMC) scaffolds in partial thickness wound healing. SCMC scaffolds were prepared by solvent-evaporation technique. Their in vitro erosion, moisture affinity, morphology, ten...

Hypoglycemic effect of quassinoids from Brucea javanica (L.) Merr (Simaroubaceae) seeds

Ethnopharmacological relevance The seeds of Brucea javanica (L.) Merr (Simaroubaceae) are recommended by traditional practitioners for the treatment of diabetes mellitus. Aim of the study To identify the compounds responsible for blood glucose lowering effect and evaluate the acute toxicity of the compounds. Materials ...