Next-Generation Immunotherapy: Integrating Cellular Therapies, Vaccines, and Nanomedicine
Details
Name: Dr. Shikha Sharma
Affiliation: Lords University
E-Mail: sharma.shikha631@gmail.com
Google Scholar: https://scholar.google.com/citations?user=GUL0yBMAAAAJ&hl=en
Orcid: https://orcid.org/0000-0002-9717-7819
Research Interests: pharmaceutical sciences, medicinal chemistry, and nanotechnology-driven drug delivery systems, design, synthesis, and biological evaluation of novel heterocyclic compounds for therapeutic applications, particularly in cancer, diabetes, microbial infections, and neurological disorders.
Research objectives：
Recent breakthroughs in immunotherapy have remarkably changed the treatment of diseases, including those in the areas of oncology, infectious diseases, and autoimmune diseases. The latest trends in research and developments are centered on the following areas of immunotherapy: immune checkpoint inhibitors (such as PD-1/L1 and CTLA-4 inhibitors), CAR-T cell therapy, cancer vaccines, and adoptive cell therapy approaches. Other emerging areas that are under investigation nowadays are personalized immunotherapy approaches, neoantigen vaccines, bispecific antibodies, oncolytic viruses, and the use of nanotechnology for immunomodulation. There is also a recent focus of research work emphasizing the need for combination therapy (chemo-immunotherapy, radiation-immunotherapy, and nanocarriers).
Keywords：
- Immunotherapy
- Immune checkpoint inhibitors
- PD-1/PD-L1
- CTLA-4
- CAR-T cell therapy
- Cancer vaccines
- Adoptive cell therapy
- Personalized immunotherapy
- Neoantigen vaccines
- Bispecific antibodies
- Oncolytic viruses
- Nanotechnology
- Immunomodulation
- Combination therapy
- Chemo-immunotherapy
- Radio-immunotherapy;
- Nanocarriers
Expected Outcomes：
Academic: Peer-reviewed publications
Co-academic leads：
Dr. Payal Bhatnagar
Affiliation: Department of Pharmaceutical Technology, School of Pharmacy, IMU University, Kuala Lumpur 57000, Malaysia
E-Mail: payalbhatnagar2020@gmail.com
Website: https://academic-members.imu.edu.my/staff_info.php?user=515
Research Interests: Wound dressing, Regenerative materials, Novel drug delivery system, Controlled drug release, Cosmetics
Dr. Neeraj K. Sethiya
Affiliation: Faculty of Pharmacy, School of Pharmaceutical and Population Health Informatics, DIT University, Dehradun 248009, Uttarakhand, India
E-Mail: drnspharma@gmail.com
Website: https://scholar.google.com/citations?user=rizDJQMAAAAJ&hl=en
Research Interests: Herbal Drug, Technology Phytochemistry, Pharmacology Pharmacognosy, Natural Products and Plant Tissue Culture
